To play american football, you need shoes adapted to your sport and fields (grass or turf).

Your shoes can have detachable cleats more adapted for grass even if we can play on  high quality synthetic field with those models.
The molded cleats are clearly more adapted for synthetic field.
Then you can have low, mid or high design shoes to answer to your needs (skill positions, linemen,...) or answer to your needs cause you have weak ankles for example after injuries.
It's important to choose the right model having in mind all those infos.